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Acetal-Derivatized Dextran: An Acid-Responsive Biodegradable Material for Therapeutic Applications

Dextran, a biocompatible, water-soluble polysaccharide, was modified at its hydroxyls with acetal moieties such that it became insoluble in water but freely soluble in common organic solvents enabling its use in the facile preparation of acid-sensitive microparticles. These particles degrade in a pH...

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Bibliografische gegevens
Hoofdauteurs: Bachelder, Eric M., Beaudette, Tristan T., Broaders, Kyle E., Dashe, Jesse, Fréchet, Jean M. J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673804/
https://ncbi.nlm.nih.gov/pubmed/18630909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja803947s
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