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Kinetic analysis of voltage-dependent potentiation and block of the glycine α3 receptor by a neuroactive steroid analogue
We examined the actions of a carboxylated analogue of pregnanolone ((3α,5β)-20-oxopregnane-3-carboxylic acid; 3αCOOH5βP) on receptors composed of glycine receptor α3 subunits, expressed in Xenopus oocytes. This analogue both inhibits and potentiates this receptor; potentiation increases with more ne...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Blackwell Science Inc
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673770/ https://ncbi.nlm.nih.gov/pubmed/19124545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.159343 |
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