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Are neuroactive steroids promising therapeutic agents in the management of acute and chronic pain?
Neuroactive steroids with potentiating effects on GABA(A) channels and inhibitory effects on T-type Ca(2+) channels which are located in peripheral sensory neurons are potent modulators of pain perception. The focus of this review is on peripheral anti-nociceptive properties of 5α- and 5β-reduced ne...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795041/ https://ncbi.nlm.nih.gov/pubmed/19577375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2009.06.001 |
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