Novel neuroactive steroid with hypnotic and T‐type calcium channel blocking properties exerts effective analgesia in a rodent model of post‐surgical pain

Lignende værker

• Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABA(A) currents, but are not neurotoxic to the developing rat brain
  af: Tesic, Vesna, et al.
  Udgivet: (2020)
• Novel neurosteroid hypnotic blocks T-type calcium channel-dependent rebound burst firing and suppresses long-term potentiation in the rat subiculum
  af: Joksimovic, Srdjan M., et al.
  Udgivet: (2019)
• Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels
  af: Tat, Quy L., et al.
  Udgivet: (2020)
• Are neuroactive steroids promising therapeutic agents in the management of acute and chronic pain?
  af: Jevtovic-Todorovic, Vesna, et al.
  Udgivet: (2009)
• Further Evidence that Inhibition of Neuronal Voltage-Gated Calcium Channels Contributes to the Hypnotic Effect of Neurosteroid Analogue, 3β-OH
  af: Tamara Timic Stamenic, et al.
  Udgivet: (2022-05-01)