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Notch signaling promotes airway mucous metaplasia and inhibits alveolar development
The airways are conduits that transport atmospheric oxygen to the distal alveolus. Normally, airway mucous cells are rare. However, diseases of the airway are often characterized by mucous metaplasia, in which there are dramatic increases in mucous cell numbers. As the Notch pathway is known to regu...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673763/ https://ncbi.nlm.nih.gov/pubmed/19369400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.029249 |
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