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Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme
The effects of Wnt7b on lung development were examined using a conditional Wnt7b-null mouse. Wnt7b-null lungs are markedly hypoplastic, yet display largely normal patterning and cell differentiation. In contrast to findings in prior hypomorphic Wnt7b models, we find decreased replication of both dev...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556060/ https://ncbi.nlm.nih.gov/pubmed/18367557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.015495 |
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