Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme

The effects of Wnt7b on lung development were examined using a conditional Wnt7b-null mouse. Wnt7b-null lungs are markedly hypoplastic, yet display largely normal patterning and cell differentiation. In contrast to findings in prior hypomorphic Wnt7b models, we find decreased replication of both dev...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rajagopal, Jayaraj, Carroll, Thomas J., Guseh, J. Sawalla, Bores, Sam A., Blank, Leah J., Anderson, William J., Yu, Jing, Zhou, Qiao, McMahon, Andrew P., Melton, Douglas A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556060/
https://ncbi.nlm.nih.gov/pubmed/18367557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.015495
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