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Identification of an Intracellular Site of Prion Conversion

Prion diseases are fatal, neurodegenerative disorders in humans and animals and are characterized by the accumulation of an abnormally folded isoform of the cellular prion protein (PrP(C)), denoted PrP(Sc), which represents the major component of infectious scrapie prions. Characterization of the me...

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Autors principals: Marijanovic, Zrinka, Caputo, Anna, Campana, Vincenza, Zurzolo, Chiara
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673690/
https://ncbi.nlm.nih.gov/pubmed/19424437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000426
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