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Identification of an Intracellular Site of Prion Conversion

Prion diseases are fatal, neurodegenerative disorders in humans and animals and are characterized by the accumulation of an abnormally folded isoform of the cellular prion protein (PrP(C)), denoted PrP(Sc), which represents the major component of infectious scrapie prions. Characterization of the me...

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Autori principali: Marijanovic, Zrinka, Caputo, Anna, Campana, Vincenza, Zurzolo, Chiara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673690/
https://ncbi.nlm.nih.gov/pubmed/19424437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000426
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