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Cyclic GMP specifically suppresses Type-Iα cGMP-dependent protein kinase expression by ubiquitination

Type I cGMP-dependent protein kinase (PKG-I) mediates nitric oxide (NO) and hormone dependent smooth muscle relaxation and stimulates smooth muscle cell-specific gene expression. Expression of PKG-I in cultured smooth muscle cells depends on culture conditions and is inhibited by inflammatory cytoki...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dey, Nupur B., Busch, Jennifer L., Francis, Sharron H., Corbin, Jackie D., Lincoln, Thomas M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673574/
https://ncbi.nlm.nih.gov/pubmed/19168131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.01.014
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