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Cyclic GMP specifically suppresses Type-Iα cGMP-dependent protein kinase expression by ubiquitination

Type I cGMP-dependent protein kinase (PKG-I) mediates nitric oxide (NO) and hormone dependent smooth muscle relaxation and stimulates smooth muscle cell-specific gene expression. Expression of PKG-I in cultured smooth muscle cells depends on culture conditions and is inhibited by inflammatory cytoki...

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Detalhes bibliográficos
Main Authors: Dey, Nupur B., Busch, Jennifer L., Francis, Sharron H., Corbin, Jackie D., Lincoln, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673574/
https://ncbi.nlm.nih.gov/pubmed/19168131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.01.014
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