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Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila

miRNA-mediated repression affects a wide range of biological processes including development and human pathologies. The GW182 protein is a key component of miRNA repression complex, recruited by Argonaute and functioning downstream to repress translation and accelerate mRNA degradation, but little i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chekulaeva, Marina, Filipowicz, Witold, Parker, Roy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673071/
https://ncbi.nlm.nih.gov/pubmed/19304924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1364909
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