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ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway

Interferon (IFN)-induced signalling pathways have essential functions in innate immune responses. In response to type I IFNs, filamin B tethers RAC1 and a Jun N-terminal kinase (JNK)-specific mitogen-activated protein kinase (MAPK) module—MEKK1, MKK4 and JNK—and thereby promotes the activation of JN...

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Detalhes bibliográficos
Main Authors: Jeon, Young Joo, Choi, Joon Seok, Lee, Jung Yun, Yu, Kyung Ryun, Kim, Sangman Michael, Ka, Seung Hyeun, Oh, Kyu Hee, Il Kim, Keun, Zhang, Dong-Er, Bang, Ok Sun, Ha Chung, Chin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672892/
https://ncbi.nlm.nih.gov/pubmed/19270716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.23
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