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Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15
Identification of the cellular mechanisms that mediate cancer cell chemosensitivity is important for developing new cancer treatment strategies. Several chemotherapeutic drugs increase levels of the posttranslational modifier ISG15, which suggests that ISGylation could suppress oncogenesis. However,...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386819/ https://ncbi.nlm.nih.gov/pubmed/22706304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61762 |
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