A Novel Androgen Receptor Splice Variant Is Upregulated during Prostate Cancer Progression and Promotes Androgen-depletion-resistant Growth

The androgen receptor (AR) plays a key role in progression to incurable androgen-ablation resistant prostate cancer (PCA). We have identified three novel AR splice variants lacking the ligand binding domain (designated as AR3, AR4 and AR5) in hormone insensitive PCA cells. AR3, one of the major spli...

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Hlavní autoři: Guo, Zhiyong, Yang, Xi, Sun, Feng, Jiang, Richeng, Linn, Douglas E., Chen, Hege, Chen, Hegang, Kong, Xiangtian, Melamed, Jonathan, Tepper, Clifford G., Kung, Hsing-Jien, Brodie, Angela M. H., Edwards, Joanne, Qiu, Yun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672822/
https://ncbi.nlm.nih.gov/pubmed/19244107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3795
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