A Novel Androgen Receptor Splice Variant Is Upregulated during Prostate Cancer Progression and Promotes Androgen-depletion-resistant Growth

The androgen receptor (AR) plays a key role in progression to incurable androgen-ablation resistant prostate cancer (PCA). We have identified three novel AR splice variants lacking the ligand binding domain (designated as AR3, AR4 and AR5) in hormone insensitive PCA cells. AR3, one of the major spli...

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Detalhes bibliográficos
Main Authors: Guo, Zhiyong, Yang, Xi, Sun, Feng, Jiang, Richeng, Linn, Douglas E., Chen, Hege, Chen, Hegang, Kong, Xiangtian, Melamed, Jonathan, Tepper, Clifford G., Kung, Hsing-Jien, Brodie, Angela M. H., Edwards, Joanne, Qiu, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672822/
https://ncbi.nlm.nih.gov/pubmed/19244107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3795
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