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miR-124 and androgen receptor signaling inhibitors repress prostate cancer growth by downregulating androgen receptor splice variants, EZH2 and Src
miR-124 targets the androgen receptor transcript, acting as a tumor suppressor to broadly limit the growth of prostate cancer (CaP). In this study, we unraveled the mechanisms through which miR-124 acts in this setting. miR-124 inhibited proliferation of CaP cells in vitro and sensitizes them to inh...
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| Publicat a: | Cancer Res |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4681619/ https://ncbi.nlm.nih.gov/pubmed/26573802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-0795 |
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