Compensatory up-regulation of tyrosine kinase Etk/BMX in response to androgen deprivation promotes castration-resistant growth of prostate cancer cells

We previously showed that targeted expression of non-receptor tyrosine kinase Etk/BMX in mouse prostate induces prostate intraepithelial neoplasia, implying a possible causal role of Etk in prostate cancer development and progression. Here, we report that Etk is upregulated in both human and mouse p...

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Autori principali: Dai, Bojie, Chen, Hege, Guo, Shengjie, Yang, Xi, Linn, Douglas E., Sun, Feng, Li, Wei, Guo, Zhiyong, Xu, Kexin, Kim, Oekyung, Kong, Xiangtian, Melamed, Jonathan, Qiu, Shaopeng, Chen, Hegang, Qiu, Yun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464488/
https://ncbi.nlm.nih.gov/pubmed/20570899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4610
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