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1.8 Å structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells

Glucocorticoid-induced TNF receptor ligand (GITRL), a prominent member of the TNF superfamily, activates its receptor on both effector and regulatory T cells to generate critical costimulatory signals that have been implicated in a wide range of T-cell immune functions. The crystal structures of mur...

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Autori principali: Chattopadhyay, Kausik, Ramagopal, Udupi A., Nathenson, Stanley G., Almo, Steven C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672815/
https://ncbi.nlm.nih.gov/pubmed/19390148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909005721
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