Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function

Glucocorticoid-induced TNF receptor ligand (GITRL), a recently identified member of the TNF family, binds to its receptor GITR on both effector and regulatory T cells and generates positive costimulatory signals implicated in a wide range of T cell functions. Structural analysis reveals that the hum...

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Detalhes bibliográficos
Main Authors: Chattopadhyay, Kausik, Ramagopal, Udupi A., Mukhopadhaya, Arunika, Malashkevich, Vladimir N., DiLorenzo, Teresa P., Brenowitz, Michael, Nathenson, Stanley G., Almo, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148310/
https://ncbi.nlm.nih.gov/pubmed/18040044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709264104
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