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Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2

Programmed death-1 (PD-1) is a member of the CD28/B7 superfamily that delivers negative signals upon interaction with its two ligands, PD-L1 or PD-L2. The high-resolution crystal structure of the complex formed by the complete ectodomains of murine PD-1 and PD-L2 revealed a 1:1 receptor:ligand stoic...

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Detalhes bibliográficos
Main Authors: Lázár-Molnár, Eszter, Yan, Qingrong, Cao, Erhu, Ramagopal, Udupi, Nathenson, Stanley G., Almo, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492495/
https://ncbi.nlm.nih.gov/pubmed/18641123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804453105
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