Programmed death-1 (PD-1)–deficient mice are extraordinarily sensitive to tuberculosis

The programmed death-1 (PD-1) costimulatory receptor inhibits T and B cell responses and plays a crucial role in peripheral tolerance. PD-1 has recently been shown to inhibit T cell responses during chronic viral infections such as HIV. In this study, we examined the role of PD-1 in infection with M...

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Detaylı Bibliyografya
Asıl Yazarlar: Lázár-Molnár, Eszter, Chen, Bing, Sweeney, Kari A., Wang, Emilie J., Liu, Weijun, Lin, Juan, Porcelli, Steven A., Almo, Steven C., Nathenson, Stanley G., Jacobs, William R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922129/
https://ncbi.nlm.nih.gov/pubmed/20624978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007394107
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