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Lithium Increases Synapse Formation between Hippocampal Neurons by Depleting Phosphoinositides
The mood-stabilizing effects of lithium are well documented, although its mechanism of action remains unknown. Increases in gray matter volume detected in patients with bipolar disorder who were treated with lithium suggest that changes in the number of synapses might underlie its therapeutic effect...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672813/ https://ncbi.nlm.nih.gov/pubmed/19188338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.052357 |
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