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Lithium Increases Synapse Formation between Hippocampal Neurons by Depleting Phosphoinositides

The mood-stabilizing effects of lithium are well documented, although its mechanism of action remains unknown. Increases in gray matter volume detected in patients with bipolar disorder who were treated with lithium suggest that changes in the number of synapses might underlie its therapeutic effect...

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Autors principals: Kim, Hee Jung, Thayer, Stanley A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Pharmacology and Experimental Therapeutics 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672813/
https://ncbi.nlm.nih.gov/pubmed/19188338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.052357
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