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Cannabinoids inhibit network-driven synapse loss between hippocampal neurons in culture

Dendritic pruning and loss of synaptic contacts are early events in many neurodegenerative diseases. These effects are dynamic and appear to differ mechanistically from the cell death process. Cannabinoids modulate synaptic activity and afford protection in some neurotoxicity models. We investigated...

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Détails bibliographiques
Auteurs principaux: Kim, Hee Jung, Waataja, Jonathan J., Thayer, Stanley A.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2398764/
https://ncbi.nlm.nih.gov/pubmed/18310474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.131607
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