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Cannabinoids inhibit network-driven synapse loss between hippocampal neurons in culture

Dendritic pruning and loss of synaptic contacts are early events in many neurodegenerative diseases. These effects are dynamic and appear to differ mechanistically from the cell death process. Cannabinoids modulate synaptic activity and afford protection in some neurotoxicity models. We investigated...

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Autores principales: Kim, Hee Jung, Waataja, Jonathan J., Thayer, Stanley A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2398764/
https://ncbi.nlm.nih.gov/pubmed/18310474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.131607
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