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Lithium Increases Synapse Formation between Hippocampal Neurons by Depleting Phosphoinositides

The mood-stabilizing effects of lithium are well documented, although its mechanism of action remains unknown. Increases in gray matter volume detected in patients with bipolar disorder who were treated with lithium suggest that changes in the number of synapses might underlie its therapeutic effect...

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Detalhes bibliográficos
Main Authors: Kim, Hee Jung, Thayer, Stanley A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672813/
https://ncbi.nlm.nih.gov/pubmed/19188338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.052357
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