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Cannabinoids inhibit network-driven synapse loss between hippocampal neurons in culture

Dendritic pruning and loss of synaptic contacts are early events in many neurodegenerative diseases. These effects are dynamic and appear to differ mechanistically from the cell death process. Cannabinoids modulate synaptic activity and afford protection in some neurotoxicity models. We investigated...

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Bibliografiske detaljer
Main Authors: Kim, Hee Jung, Waataja, Jonathan J., Thayer, Stanley A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2398764/
https://ncbi.nlm.nih.gov/pubmed/18310474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.131607
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