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ABT-737 Synergizes with Chemotherapy to Kill Head and Neck Squamous Cell Carcinoma Cells via a Noxa-Mediated Pathway

Overexpression of Bcl-X(L), an antiapoptotic Bcl-2 family member, occurs in a majority of head and neck squamous cell carcinomas (HNSCCs) and correlates with chemotherapy resistance in this disease. Overexpression of Bcl-2 is also observed in HNSCC, albeit less frequently. We have previously shown t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Rongxiu, Zang, Yan, Li, Changyou, Patel, Neil S., Grandis, Jennifer R., Johnson, Daniel E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Pharmacology and Experimental Therapeutics 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672802/
https://ncbi.nlm.nih.gov/pubmed/19246337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.052969
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