Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation

Enterohemorrhagic Escherichia coli O157:H7 translocates 2 effectors to trigger localized actin assembly in mammalian cells, resulting in filamentous actin “pedestals.” One effector, the translocated intimin receptor (Tir), is localized in the plasma membrane and clustered upon binding the bacterial...

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Main Authors: Vingadassalom, Didier, Kazlauskas, Arunas, Skehan, Brian, Cheng, Hui-Chun, Magoun, Loranne, Robbins, Douglas, Rosen, Michael K., Saksela, Kalle, Leong, John M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672544/
https://ncbi.nlm.nih.gov/pubmed/19366662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809131106
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