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Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation

Enterohemorrhagic Escherichia coli O157:H7 translocates 2 effectors to trigger localized actin assembly in mammalian cells, resulting in filamentous actin “pedestals.” One effector, the translocated intimin receptor (Tir), is localized in the plasma membrane and clustered upon binding the bacterial...

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Detalhes bibliográficos
Main Authors: Vingadassalom, Didier, Kazlauskas, Arunas, Skehan, Brian, Cheng, Hui-Chun, Magoun, Loranne, Robbins, Douglas, Rosen, Michael K., Saksela, Kalle, Leong, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672544/
https://ncbi.nlm.nih.gov/pubmed/19366662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809131106
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