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Structural Mechanism of WASP Activation by the Enterohaemorrhagic E. coli Effector EspF(U)
During infection enterohaemorrhagic Escherichia coli (EHEC) usurp the actin cytoskeleton of eukaryotic cells by injecting the EspF(U) protein into the host cytoplasm1, 2. EspF(U) controls actin by activating members of the Wiskott-Aldrich Syndrome Protein (WASP) family1–5. Here we show that EspF(U)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719906/ https://ncbi.nlm.nih.gov/pubmed/18650809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07160 |
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