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Dense genome-wide SNP linkage scan in 301 hereditary prostate cancer families identifies multiple regions with suggestive evidence for linkage

The search for susceptibility loci in hereditary prostate cancer (HPC) has proven challenging due to genetic and disease heterogeneity. Multiple risk loci have been identified to date, however few loci have been replicated across independent linkage studies. In addition, most previous analyses have...

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Autores principales: Stanford, Janet L., FitzGerald, Liesel M., McDonnell, Shannon K., Carlson, Erin E., McIntosh, Laura M., Deutsch, Kerry, Hood, Lee, Ostrander, Elaine A., Schaid, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671990/
https://ncbi.nlm.nih.gov/pubmed/19251732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp100
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