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Genome-wide linkage analyses of hereditary prostate cancer families with colon cancer provide further evidence for a susceptibility locus on 15q11–q14

The search for susceptibility loci in hereditary prostate cancer (HPC) is challenging because of locus and disease heterogeneity. One approach to reduce disease heterogeneity is to stratify families on the basis of the occurrence of multiple cancer types. This method may increase the power for detec...

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Autors principals: FitzGerald, Liesel M, McDonnell, Shannon K, Carlson, Erin E, Langeberg, Wendy, McIntosh, Laura M, Deutsch, Kerry, Ostrander, Elaine A, Schaid, Daniel J, Stanford, Janet L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921483/
https://ncbi.nlm.nih.gov/pubmed/20407467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.49
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