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Searching for Epistasis and Linkage Heterogeneity by Correlations of Pedigree-Specific Linkage Scores

Recognizing that multiple genes are likely responsible for common complex traits, statistical methods are needed to rapidly screen for either interacting genes or locus heterogeneity in genetic linkage data. To achieve this, some investigators have proposed examining the correlation of pedigree link...

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Detalhes bibliográficos
Main Authors: Schaid, Daniel J., McDonnell, Shannon K., Carlson, Erin E., Thibodeau, Stephen N., Stanford, Janet L., Ostrander, Elaine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674316/
https://ncbi.nlm.nih.gov/pubmed/18330905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20319
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