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Searching for Epistasis and Linkage Heterogeneity by Correlations of Pedigree-Specific Linkage Scores

Recognizing that multiple genes are likely responsible for common complex traits, statistical methods are needed to rapidly screen for either interacting genes or locus heterogeneity in genetic linkage data. To achieve this, some investigators have proposed examining the correlation of pedigree link...

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Autores principales: Schaid, Daniel J., McDonnell, Shannon K., Carlson, Erin E., Thibodeau, Stephen N., Stanford, Janet L., Ostrander, Elaine A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674316/
https://ncbi.nlm.nih.gov/pubmed/18330905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20319
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