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Family-based association analysis of 42 hereditary prostate cancer families identifies the Apolipoprotein L3 region on chromosome 22q12 as a risk locus

Multiple genome-wide scans for hereditary prostate cancer (HPC) have identified susceptibility loci on nearly every chromosome. However, few results have been replicated with statistical significance. One exception is chromosome 22q, for which five independent linkage studies yielded strong evidence...

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Detalhes bibliográficos
Main Authors: Johanneson, Bo, McDonnell, Shannon K., Karyadi, Danielle M., Quignon, Pascale, McIntosh, Laura, Riska, Shaun M., FitzGerald, Liesel M., Johnson, Gregory, Deutsch, Kerry, Williams, Gabrielle, Tillmans, Lori S., Stanford, Janet L., Schaid, Daniel J., Thibodeau, Stephen N., Ostrander, Elaine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935853/
https://ncbi.nlm.nih.gov/pubmed/20631155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq283
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