Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer susceptibility genes

Prostate cancer (PCa) susceptibility is defined by a continuum from rare, high-penetrance to common, low-penetrance alleles. Research to date has concentrated on identification of variants at the ends of that continuum. Taking an alternate approach, we focused on the important but elusive class of l...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Karyadi, Danielle M., Geybels, Milan S., Karlins, Eric, Decker, Brennan, McIntosh, Laura, Hutchinson, Amy, Kolb, Suzanne, McDonnell, Shannon K., Hicks, Belynda, Middha, Sumit, FitzGerald, Liesel M., DeRycke, Melissa S., Yeager, Meredith, Schaid, Daniel J., Chanock, Stephen J., Thibodeau, Stephen N., Berndt, Sonja I., Stanford, Janet L., Ostrander, Elaine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341753/
https://ncbi.nlm.nih.gov/pubmed/27902461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13646
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