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Pathologic Prion Protein Infects Cells by Lipid-Raft Dependent Macropinocytosis

Transmissible spongiform encephalopathies, including variant-Creutzfeldt-Jakob disease (vCJD) in humans and bovine spongiform encephalopathies in cattle, are fatal neurodegenerative disorders characterized by protein misfolding of the host cellular prion protein (PrP(C)) to the infectious scrapie fo...

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Autors principals: Wadia, Jehangir S., Schaller, Monica, Williamson, R. Anthony, Dowdy, Steven F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671965/
https://ncbi.nlm.nih.gov/pubmed/19390657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003314
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