Loading...
Affinity modulation of small-molecule ligands by borrowing endogenous protein surfaces
A general strategy is described for improving the binding properties of small-molecule ligands to protein targets. A bifunctional molecule is created by chemically linking a ligand of interest to another small molecule that binds tightly to a second protein. When the ligand of interest is presented...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
1999
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC26718/ https://ncbi.nlm.nih.gov/pubmed/10051576 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|