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Site-Selective Glycosylation of Hemoglobin on Cys β93
In this work, we describe the synthesis and characterization of a novel glycosylated hemoglobin (Hb) with high oxygen affinity as a potential Hb-based oxygen carrier. Site-selective glycosylation of bovine Hb was achieved by conjugating a lactose derivative to Cys 93 on the β subunit of Hb. LC-MS an...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671398/ https://ncbi.nlm.nih.gov/pubmed/18925771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc8003205 |
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