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Site-Selective Glycosylation of Hemoglobin on Cys β93

In this work, we describe the synthesis and characterization of a novel glycosylated hemoglobin (Hb) with high oxygen affinity as a potential Hb-based oxygen carrier. Site-selective glycosylation of bovine Hb was achieved by conjugating a lactose derivative to Cys 93 on the β subunit of Hb. LC-MS an...

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書誌詳細
主要な著者: Zhang, Yalong, Bhatt, Veer S., Sun, Guoyong, Wang, Peng G., Palmer, Andre F.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671398/
https://ncbi.nlm.nih.gov/pubmed/18925771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc8003205
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