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Interferon-γ Prevents Death of Bystander Neurons during CD8 T Cell Responses in the Brain

T cells restricted to neurotropic viruses are potentially harmful as their activity may result in the destruction of neurons. In the Borna disease virus (BDV) model, antiviral CD8 T cells entering the brain of infected mice cause neurological disease but no substantial loss of neurons unless the ani...

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Hlavní autoři: Richter, Kirsten, Hausmann, Jürgen, Staeheli, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671268/
https://ncbi.nlm.nih.gov/pubmed/19359516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080897
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