CD8 T Cells Require Gamma Interferon To Clear Borna Disease Virus from the Brain and Prevent Immune System-Mediated Neuronal Damage

Borna disease virus (BDV) frequently causes meningoencephalitis and fatal neurological disease in young but not old mice of strain MRL. Disease does not result from the virus-induced destruction of infected neurons. Rather, it is mediated by H-2(k)-restricted antiviral CD8 T cells that recognize a p...

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Bibliografiske detaljer
Main Authors: Hausmann, Jürgen, Pagenstecher, Axel, Baur, Karen, Richter, Kirsten, Rziha, Hanns-Joachim, Staeheli, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262614/
https://ncbi.nlm.nih.gov/pubmed/16227271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.21.13509-13518.2005
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