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Activation of Insulin-Reactive CD8 T-Cells for Development of Autoimmune Diabetes
OBJECTIVE: We have previously reported a highly diabetogenic CD8 T-cell clone, G9C8, in the nonobese diabetic (NOD) mouse, specific to low-avidity insulin peptide B15-23, and cells responsive to this antigen are among the earliest islet infiltrates. We aimed to study the selection, activation, and d...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671054/ https://ncbi.nlm.nih.gov/pubmed/19208910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0800 |
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