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Combination Treatment With Anti-CD20 and Oral Anti-CD3 Prevents and Reverses Autoimmune Diabetes

Type 1 diabetes (T1D) is a T cell–mediated autoimmune disease, although B cells also play an important role in T1D development. Both T cell– and B cell–directed immunotherapies have shown efficacy in the prevention and reversal of T1D. However, whether the combined strategy of targeting both T and B...

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Detalhes bibliográficos
Main Authors: Hu, Changyun, Ding, Heyuan, Zhang, Xiaojun, Wong, F. Susan, Wen, Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717853/
https://ncbi.nlm.nih.gov/pubmed/23447122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1175
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