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Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice
The precise roles of B cells in promoting the pathogenesis of type 1 diabetes remain undefined. Here, we demonstrate that B cell depletion in mice can prevent or delay diabetes, reverse diabetes after frank hyperglycemia, and lead to the development of cells that suppress disease. To determine the e...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2096456/ https://ncbi.nlm.nih.gov/pubmed/18060033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32405 |
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