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Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice
OBJECTIVE: Interleukin (IL)-21 is a type 1 cytokine that has been implicated in the pathogenesis of type 1 diabetes via the unique biology of the nonobese diabetic (NOD) mouse strain. The aim of this study was to investigate a causal role for IL-21 in type 1 diabetes. RESEARCH DESIGN AND METHODS: We...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671036/ https://ncbi.nlm.nih.gov/pubmed/19208913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0882 |
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