Metabolically inactive insulin analogue does not prevent autoimmune diabetes in NOD mice

AIMS/HYPOTHESIS: Insulin is widely considered to be a driver antigen in type 1 diabetes in humans and in mouse models of the disease. Therefore, insulin or insulin analogues are candidates for tolerogenic drugs to prevent disease onset in individuals with risk of diabetes. Previous experiments have...

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Detaylı Bibliyografya
Yayımlandı:Diabetologia
Asıl Yazarlar: Grönholm, Juha, Pagni, Philippe P., Pham, Minh N., Gibson, Claire B., Macomber, Paul F., Vela, José Luis, von Herrath, Matthias, Lenardo, Michael J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661969/
https://ncbi.nlm.nih.gov/pubmed/28455654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-017-4276-5
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