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Development of Translational Pharmacokinetic–Pharmacodynamic Models

Contemporary models in the field of pharmacokinetic–pharmacodynamic (PK–PD) modeling often incorporate the fundamental principles of capacity limitation and operation of turnover processes to describe the time course of pharmacological effects in mechanistic terms. This permits the identification of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Mager, DE, Jusko, WJ
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671003/
https://ncbi.nlm.nih.gov/pubmed/18388873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2008.52
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