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Development of Translational Pharmacokinetic–Pharmacodynamic Models
Contemporary models in the field of pharmacokinetic–pharmacodynamic (PK–PD) modeling often incorporate the fundamental principles of capacity limitation and operation of turnover processes to describe the time course of pharmacological effects in mechanistic terms. This permits the identification of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671003/ https://ncbi.nlm.nih.gov/pubmed/18388873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2008.52 |
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