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Population Pharmacokinetic/Pharmacodynamic Modeling of Systemic Corticosteroid Inhibition of Whole Blood Lymphocytes: Modeling Interoccasion Pharmacodynamic Variability
PURPOSE: To develop a population pharmacokinetic/pharmacodynamic (PK/PD) model that characterizes the effects of major systemic corticosteroids on lymphocyte trafficking and responsiveness. MATERIALS AND METHODS: Single, presumably equivalent, doses of intravenous hydrocortisone (HC), dexamethasone...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4181339/ https://ncbi.nlm.nih.gov/pubmed/17385022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-006-9232-x |
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