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Control of telomere length by a trimming mechanism that involves generation of t-circles
Telomere lengths are maintained in many cancer cells by the ribonucleoprotein enzyme telomerase but can be further elongated by increasing telomerase activity through the overexpression of telomerase components. We report here that increased telomerase activity results in increased telomere length t...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670870/ https://ncbi.nlm.nih.gov/pubmed/19214183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.42 |
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