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Control of telomere length by a trimming mechanism that involves generation of t-circles

Telomere lengths are maintained in many cancer cells by the ribonucleoprotein enzyme telomerase but can be further elongated by increasing telomerase activity through the overexpression of telomerase components. We report here that increased telomerase activity results in increased telomere length t...

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Detalles Bibliográficos
Main Authors: Pickett, Hilda A, Cesare, Anthony J, Johnston, Rebecca L, Neumann, Axel A, Reddel, Roger R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670870/
https://ncbi.nlm.nih.gov/pubmed/19214183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.42
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